Description
The DOTA molecule is a powerful chelating agent used in nuclear medicine to bind a radioactive tracer, most commonly Gallium-68 (68Ga). This combination forms a stable complex known as a Ga-68 DOTA radiotracer, which is injected into the body for PET imaging.
Once administered, the Ga-68 DOTA compound binds specifically to cells that express somatostatin receptors. These receptors are commonly found on neuroendocrine tumors (NETs), allowing the scan to precisely locate and evaluate these tumors.
What Is a Ga-68 DOTA PET Scan?
A Ga-68 DOTA PET scan is a type of Positron Emission Tomography (PET) imaging that uses a DOTA-based radiotracer to detect and map somatostatin receptor–positive tumors. It provides high-resolution, whole-body images that help doctors identify even small or early-stage neuroendocrine tumors.
Why Is Ga-68 DOTA PET Imaging Performed?
This scan is recommended to:
- Detect and locate neuroendocrine tumors
- Determine the extent of disease spread
- Assess eligibility for targeted radionuclide therapy
- Monitor response to treatment
- Identify tumor recurrence
How Is a Ga-68 DOTA PET Scan Performed?
A small amount of Ga-68 DOTA radiotracer is injected into a vein. After a short waiting period to allow the tracer to bind to tumor cells, the patient lies on the PET scanner while detailed images are taken.
The procedure is painless and usually takes about 30 to 60 minutes.
Advantages of Ga-68 DOTA PET Imaging
- Highly sensitive detection of neuroendocrine tumors
- Excellent tumor localization and staging
- Supports personalized and targeted therapy planning
- Non-invasive and safe
Book Ga-68 DOTA PET Scan
If neuroendocrine tumors are suspected or need follow-up, a Ga-68 DOTA PET scan provides precise and reliable imaging to guide diagnosis and treatment decisions.

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